What is that building that Second Ave is dead-ending into?
The Wabash railroad and terminal building was in this location. The buildings were torn down to make way for Gateway Center and Point State Park redevelopment. Here is a great resource for historic maps in PA. Zoom into Pittsburgh and select which generation of maps you want to view. http://www.pennpilot.psu.edu/
This has to be near the other Chas Bonini Pittsburg Ice Cream picture. It seems that this is oriented to look southeast.